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準備投藥으로서 Valium, Pentobarbital의 臨床的效果에 關한 硏究
STUDIES ON THE CLINICAL EFFICACY OF VALIUM AND PENTOBARBITAL AS PREMEDICATING AGENT

대한소아치과학회지 1978년 5권 1호 p.76 ~ 82

소속 상세정보

김영진(金永進)/Young Jin Kim

KMID : 0358919780050010076

Abstract

著者는 小兒齒科患者 45名을 對象으로 準備投藥으로서의 Valium, Sodium pentobarbital,
Placebo의 臨床的效果를 比較해 본 結果 다음과 같은 結論을 얻었다.
1. Valium(3∼5mg), Sodium Pentobarbital(30∼70mg)은 Placebo(僞藥)과 比較時兒童取扱
上의 效果는 있었으나 統計學的有意性은 認知할 수 없었다.
2. Tense cooperative兒童에 있어서 Valium과 Pentobarbital은 僞藥보다 兒童取扱上高度의
有意性을 나타냈다.
.3. 治療時兒動의 行動調節은 初期(15分)에서 Valium, Pentobarbital間에 多少의 差가 있었
으나 時間의 經過에 따라 減少했고 初期에서는 Pentobarbital이 가장 優秀했다.
4. Pentobarbital群에서 2名이 逆反應(Paradoxical excitement)을 나타냈고 약간의 假眠現象
外의 副作用은 없었다.
5. Valium과 Pentobarbital이 모든 患者에 있어서 兒童取扱上效果가 恒常優秀하게 나타나
지는 않았다.
#초록#
To evaluate clinically effect of Valium and Sodium pentobarbital as premedicating
agent, both drugs and a placebo were compared in 45 patients (2 to 11 yrs).
The results were as follows
1. Both Sodium pentobarbital and Valium were superior to placebo for control of
crying, cooperation and apprehension, but the statistically differences were not
significant.
2. Both Valium and Sodium pentobarbital were superior to placebo for control of
behavior in tense cooperative child; the differences were significant statistically.
3. The difference between Pentobarbital and Valium were more pronounced at the
initial level than at the subsequent readings, and Sodium pentobarbital was for superior
at the initial level to the other drugs.
4. Paradoxical excitement occurred in 2 cases on the Sodium pentobarbital group, and
other apparent side effect did not occur, excluding mild drowsiness.
5. Neither Valium nor Sodium pentobarbital, as used in this study, resulted in
consistantly better behavior in all patients.